Sensing of biologically relevant d-metal ions using a Eu(III)-cyclen based luminescent displacement assay in aqueous pH 7.4 buffered solution.
نویسندگان
چکیده
1·Eu·BPS was developed as a luminescent lanthanide sensor for use in displacement assays for detection of d-metal ions by monitoring the changes in the europium emission, which was quenched for iron(II), with a detection limit of ∼10 pM (0.002 μg L(-1)) for Fe(II) in buffered pH 7.4 solution.
منابع مشابه
Sensing of biologically relevant d-metal ions using a Eu(III)-cyclen based luminescent displacement assay in aqueous pH 7.4 buffered solutionw
Over the past decades the importance of metals in biology has been increasingly recognised. Approximately one third of the human proteome contains metal cations, either in the form of cofactors, with catalytic function, or as structural support elements. Moreover, a growing number of diseases have been identified that are characterised by metal imbalance in cells and tissues. Hence, the identif...
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 24 شماره
صفحات -
تاریخ انتشار 2011